SOCIETY FOR BRAIN MAPPING AND THERAPEUTICS

BREAKING BOUNDARIES OF SCIENCE, TECHNOLOGY, MEDICINE, ART & HEALTHCARE POLICY

In module 4, you should have learned how DTI maps white matter pathways, providing insights into brain connectivity and structural integrity. The module explored clinical and research applications in trauma, developmental disorders, and psychiatric conditions while addressing challenges like noise and artifacts in data interpretation.


Instructions:

  1. Read each question carefully before answering.
  2. For Multiple Choice Questions, select the best answer by choosing A, B, C, or D.
  3. For True/False Questions, indicate whether the statement is True or False.
  4. For Fill-in-the-Blank Questions, write the most accurate word or phrase to complete the sentence.
  5. Take your time to reflect on the concepts and review your answers if needed.

Understanding White Matter Tractography


Diffusion of Water Molecules

Water molecules diffuse more freely along the direction of fibers in the brain.

DTI measures the and extent of water diffusion, providing data on white matter tract orientation.


Tensor Representation

DTI uses a mathematical model called a to describe the diffusion pattern of water molecules.

The tensor provides critical information about the and degree of water diffusion along axons.


Tractography Algorithms


Applications of White Matter Tractography

Disruptions in white matter tracts can be associated with neurological conditions such as and traumatic brain injury.

By visualizing white matter tracts, researchers can map major pathways such as the tract and the corpus callosum.


Real-World Example: Stroke Rehabilitation & MS