Quiz 4

In module 4, you should have learned how DTI maps white matter pathways, providing insights into brain connectivity and structural integrity. The module explored clinical and research applications in trauma, developmental disorders, and psychiatric conditions while addressing challenges like noise and artifacts in data interpretation.

Instructions:

  1. Read each question carefully before answering.
  2. For Multiple Choice Questions, select the best answer by choosing A, B, C, or D.
  3. For True/False Questions, indicate whether the statement is True or False.
  4. For Fill-in-the-Blank Questions, write the most accurate word or phrase to complete the sentence.
  5. Take your time to reflect on the concepts and review your answers if needed.

Understanding White Matter Tractography

What is the primary purpose of white matter tractography? *
Which part of the brain consists of nerve fibers that facilitate communication between regions? *
White matter tractography focuses on mapping gray matter regions in the brain. *
DTI allows researchers to visualize white matter tracts in vivo, meaning within the living brain. *

Diffusion of Water Molecules

Water molecules diffuse more freely along the direction of __________ fibers in the brain. *

Water molecules diffuse more freely along the direction of fibers in the brain.

DTI measures the __________ and extent of water diffusion, providing data on white matter tract orientation. *

DTI measures the and extent of water diffusion, providing data on white matter tract orientation.

Why does water diffusion in white matter provide valuable information? *

Tensor Representation

The diffusion of water molecules is uniform in all directions within the brain. *
DTI uses a mathematical model called a __________ to describe the diffusion pattern of water molecules. *

DTI uses a mathematical model called a to describe the diffusion pattern of water molecules.

The tensor provides critical information about the __________ and degree of water diffusion along axons. *

The tensor provides critical information about the and degree of water diffusion along axons.

Tractography Algorithms

What role do tractography algorithms play in DTI? *
Tractography algorithms reconstruct and visualize white matter tracts from DTI data. *

Applications of White Matter Tractography

Disruptions in white matter tracts can be associated with neurological conditions such as __________ and traumatic brain injury. *

Disruptions in white matter tracts can be associated with neurological conditions such as and traumatic brain injury.

By visualizing white matter tracts, researchers can map major pathways such as the __________ tract and the corpus callosum. *

By visualizing white matter tracts, researchers can map major pathways such as the tract and the corpus callosum.

How is DTI used in stroke rehabilitation? *
In multiple sclerosis (MS), DTI can: *

Real-World Example: Stroke Rehabilitation & MS

DTI is used to track neural recovery in stroke patients undergoing rehabilitation. *
In MS patients, DTI shows changes in brain connectivity that help understand disease progression. *