Quiz 2:

In module 2, we explored the principles and applications of fMRI, including task-based and resting-state imaging. We learned how fMRI detects brain activity through BOLD signals, with clinical uses in diagnosing stroke, epilepsy, and psychiatric disorders. Real-world case studies demonstrate its role in recovery and surgical planning.

Instructions:

  1. Read each question carefully before answering.
  2. For Multiple Choice Questions, select the best answer by choosing A, B, C, or D.
  3. For True/False Questions, indicate whether the statement is True or False.
  4. For Fill-in-the-Blank Questions, write the most accurate word or phrase to complete the sentence.
  5. Take your time to reflect on the concepts and review your answers if needed.

Principles of fMRI

The BOLD signal in fMRI directly measures electrical activity in neurons. *
What is the main principle behind the BOLD signal in fMRI? *
Functional MRI (fMRI) measures brain activity by detecting changes in __________ levels. *

Functional MRI (fMRI) measures brain activity by detecting changes in levels.

Hemodynamic response occurs immediately after neural activity with no delay. *
The delay of the hemodynamic response to peak after a stimulus is approximately __________ seconds. *

The delay of the hemodynamic response to peak after a stimulus is approximately seconds.

Techniques for Measuring Brain Activity

In resting-state fMRI, brain activity is measured when the participant is __________. *

In resting-state fMRI, brain activity is measured when the participant is .

Using task-based fMRI, researchers can identify specific brain regions involved in functions such as __________ and motor skills. *

Using task-based fMRI, researchers can identify specific brain regions involved in functions such as and motor skills.

What is one key use of resting-state fMRI? *
In clinical settings, task-based fMRI can be used for: *
Task-based fMRI helps identify brain regions activated by specific tasks, such as solving puzzles or language processing. *

Clinical Applications of fMRI

fMRI has clinical applications in diagnosing __________ by pinpointing the location of seizure foci for surgical intervention. *

fMRI has clinical applications in diagnosing by pinpointing the location of seizure foci for surgical intervention.

Clinical fMRI can help map critical brain areas before surgeries, minimizing post-operative deficits. *
Altered connectivity in the Default Mode Network (DMN) is often associated with __________. *

Altered connectivity in the Default Mode Network (DMN) is often associated with .

Which condition is often studied using resting-state fMRI to detect altered brain connectivity? *
Resting-state fMRI is useful for studying brain connectivity patterns in psychiatric conditions like depression. *

Case Studies: fMRI in Neurological Disorders

What key finding was observed in TBI patients during task-based fMRI recovery studies? *
Task-based fMRI is helpful in mapping motor areas before brain surgery for epilepsy patients. *
Resting-state fMRI studies have contributed to early detection strategies for Alzheimer’s disease. *