Latest Clinical Trials

New Treatment for 'Arthritis of the Spine' Prevents Paralysis

Toronto, Canada (September 18, 2013) – In a world-first, decompression surgery has been shown to be an effective procedure to treat cervical spondylotic myelopathy (CSM) – a common progressive, degenerative disease of the spine that can lead to paralysis – according to the results of a multi-centre clinical trial published today.

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Can we predict Alzheimer's a decade before symptoms?

Can we predict Alzheimer's a decade before symptoms? - CNN.com

Dr. Sanjay Gupta, CNN Chief Medical Correspondent (August 18, 2013) – Researchers developed a test to check the retina for signs of Alzheimer's. Trial is looking at whether this test can identify patients before symptoms begin. This research is important, because 1 in 8 people who are 65 and older have Alzheimer's disease, and the incidence of the disease is expected to nearly triple by 2050 as the number of older Americans grows.

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Galaxy-Exploring Camera to Be Used in the Operating Room

Galaxy-Exploring Camera to Be Used in the Operating Room

ScienceDaily.com (July 12, 2012) – Neurosurgeons and researchers at Cedars-Sinai Medical Center and the Maxine Dunitz Neurosurgical Institute are adapting an ultraviolet camera to possibly bring planet-exploring technology into the operating room.

If the system works when focused on brain tissue, it could give surgeons a real-time view of changes invisible to the naked eye and unapparent even with magnification of current medical imaging technologies. The pilot study seeks to determine if the camera provides visual detail that might help surgeons distinguish areas of healthy brain from deadly tumors called gliomas, which have irregular borders as they spread into normal tissue.

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Vaccine offers hope for Cancer patients

Galaxy-Exploring Camera to Be Used in the Operating Room

Dr. Sanjay Gupta, CNN Chief Medical Correspondent (August 8, 2012) – A new vaccine offers patients diagnosed with a common and aggressive type of brain cancer some hope.

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ReACT: A Phase 2 Study of Rindopepimut (CDX-110) plus Bevacizumab in Relapsed Glioblastoma

ReACT: A Phase 2 Study of Rindopepimut (CDX-110) plus Bevacizumab in Relapsed Glioblastoma

A 65 year old otherwise healthy female presented with seizure in May of 2011 and was found to have a large left frontal mass (Figure 1A). It was gross totally resected at an outside hospital and the pathology revealed glioblastoma (GBM). She underwent concurrent radiation and chemotherapy including Bevacizumab and Temozolomide at an outside institution. Her platelet counts initially dropped so Bevacizumab was discontinued but they recovered enough so that she did receive adjuvant monthly Temozolomide after her chemoradiation. The patient suffered two breakthrough seizures in March of 2012 and an MRI revealed recurrent disease at the site of the initial resection cavity (Figure 1B). She underwent a re-resection with gross total resection at Stanford University (Figure 1C). Pathology revealed radiation necrosis and recurrent glioblastoma (MGMT positive). EGFRvIII testing was performed and the tumor was positive for the EGFRvIII mutation.

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